By: Sandra Linder

Another Soltesz Lab reunion at AES in the books.

In 2023, Jordan became a faculty member and started his own lab in Neurology at Harvard Medical School and the Rosamund Stone Zander Translational Neuroscience Center and F.M. Kirby Neurobiology Center at Boston Children’s Hospital. His lab aims to understand how basic mechanisms that support healthy brain functions become hijacked in epilepsy to drive pathophysiology.  His lab’s most recent focus is unravelling how local circuit and large-scale network mechanisms, which normally control memory processes, become substrates for hypersynchronous, pathological activity in epilepsy. To translate their findings, his group develops non-invasive ultrasound approaches to re-tune neural circuits with high spatial and cell type-specific precision.

Florian completed his PhD in Neuroscience with Dr. Jean Christophe Poncer at Sorbonne University (Paris). During his PhD, he explored the mechanisms regulating the expression and function of the K+/Cl- transporter type 2 (KCC2) in the brain and investigated the therapeutic potential of targeting this transporter in temporal lobe epilepsy (TLE). He is excited going the lab and will focus more specifically on the mechanisms underlying pathological ensemble activities in the epileptic brain.

Ivan Soltesz and his colleagues have found that a marijuana-like chemical in the brain calms epileptic seizures but also increases memory loss. […]

Mahad is a medical student at Stanford. He graduated from the University of Washington with a B.S. in Neuroscience. He now plan to work with Dr. Farrell to investigate the role of the medial mamillary body in spatial cognition, as well as in the encoding and retrieval of memory.