Addiction. 2019 Aug;114(8):1343-1345. doi: 10.1111/add.14540. Epub 2019 Jan 18. PubMed PMID: 30589476; PubMed Central PMCID: PMC6597308.

A growing body of evidence highlights that the endogenous cannabinoid (endocannabinoid) system is a key target for seizure control. Plant‐derived cannabinoids have several endocannabinoid and related mechanisms that may be fundamental to their anti‐seizure properties.